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Protein A Resin Market Overview
Protein A resin market size was valued at $1,037 million in 2020, and is anticipated to grow at a CAGR of 5.2% during the forecast period 2021-2026. The protein A resin industry growth rate is attributed to the increase in awareness and rising prevalence of research in monoclonal antibodies. Protein A chromatography is the most frequently used affinity chromatography method in bio-manufacturing. It is the standard technique for capturing recombinant monoclonal antibodies, which relies on the reversible and specific binding between the immobilized protein A ligand and antibodies. Protein A Resin can also be used for immunoprecipitation of proteins, protein complexes or antigens. The recombinant protein A ligand is coupled to 4% agarose. The coupling is optimized to give high binding capacity for immunoglobulins. The static binding capacity of Protein A Resin is greater than 20 mg human IgG/ml settled resin. The dynamic binding capacity will vary depending on several factors such as target antibody, flow rate etc. Apart from this, in a recent study conducted by the European Medicine Agency, in 2019, around 66 new medicines and 30 new active substances were approved in the Europe; which in turn support’s the fact that there is a high growing consciousness amongst the population that has fostered the demand for protein A resin products. However, high cost of Protein A Resin products purification are among the major factors obstructing market development during the forecast period 2021-2026.
Protein A Resin Market Report Coverage
The report: “Protein A Resin Market Forecast (2021-2026)”, by Industry ARC, covers an in-depth analysis of the following segments of the Protein A Resin market:
By Matrix Type: Agarose-based Protein A, Glass/Silica-based Protein A, and Organic Polymer-based Protein A.
By Source Types: Recombinant Protein A and Natural Protein A.
By Application: Immunoprecipitation (IP) and Antibody Purification.
By End User: Biopharmaceutical Manufacturers, Clinical Research Laboratories and Academic Institutes.
By Geography: North America (U.S, Canada, Mexico), Europe (Germany, UK, France, Italy, Spain, Russia and Others), APAC (China, Japan, India, South Korea, Australia and Others), South America(Brazil, Argentina and Others) and RoW (Middle East and Africa).
Key Takeaways
- The factors such as rise in awareness regarding various Protein A Resins owing to rising demand for mAb are amongst the major factor projected to impel growth of protein A resin market.
- Additionally, factors such as rise in the demand in therapeutics for antibodies and increasing number of research and development activities are to create opportunities paving a way for the growth in the market during forecast period 2021-2026.
Global Protein A Resin Market, By Application 2020(%)
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Protein A Resin Market Segment Analysis - By Application
In 2020, on the basis of application, antibody purification segment accounted for the largest segmental revenue of the protein A resin market. The antibody purification held the largest market on account of the fact that this form of purification is rising in demand amongst various end users be it therapeutic or for research purposes. Also, there is commercial production and purification of mAb owing to the increasing demand for monoclonal antibodies hence, the antibody form of purification is to supplement the segment development. On the contrary, immunoprecipitation segment is projected to witness healthy growth throughout the forecast period 2021-2026 with a CAGR of 5.80% since the usage of immunoprecipitation has been on the upswing owing to the fact that it’s proved efficient in the identification of S-glutathionylation in target proteins. Furthermore, its technical advancements and increased practical usages is poised to fuel the sector growth in the application segment during the forecast period 2021-2026.
Protein A Resin Market Segment Analysis - By End User
On the basis of end user, biopharmaceutical manufacturers segment accounted for the largest segmental revenue of the Protein A Resin market in 2020. The large share can be attributed to the global rise in the number’s for R&D expenditure of pharmaceutical and biopharmaceutical companies is attributed to positively affect market growth during the forecast period 2021-2026. On the other hand, clinical research laboratories segment is projected to dominate over the forecast period 2021-2026 with a CAGR of 5.50%. The clinical research laboratories are to witness a healthy growth owing to the fact that the increasing usage of various automated dispensing cabinets to enhance productivity and efficiency has been driving the clinical research laboratories segment across the globe. Furthermore, one of the major factors contributing to its fastest growth is the increased investment in clinical research laboratories infrastructures are anticipated to stimulate market growth during the forecast period 2021-2026.
Protein A Resin Market Segment Analysis - By Geography
North America is the major region dominating the Protein A Resin market with a market share of 34.89% in the year 2020. This can be attributed to the fact that the presence of well-established infrastructure, key market players as well the constantly investing into research and development activities. Furthermore, rising prevalence of chronic diseases coupled with increasing demand of technologically advanced products favor the U.S. protein A resins market growth, which further fuels the regional market.
However, Asia-Pacific is projected to be the significant-growing market during the forecast period 2021-2026 as several countries such as India and China has a rising prevalence of various government initiatives followed by enhanced pharmaceutical companies markets which is poised to propel the market growth throughout the protein A resin market forecast period 2021-2026.
Protein A Resin Market Drivers
Rapid Increase In Demand For Therapeutic Antibodies
The Protein A Resin market is poised to receive upswing owing to the rapid increase in demand for therapeutic antibodies including neurological, autoimmune, and inflammatory disorders that has resulted in all major pharmaceutical companies focusing on the R&D of therapeutic antibodies. Hence, there is a rising use of chromatography resins in drug discovery and research industry and is to propel the market growth over the forecast period 2021-2026.
Protein A Resin Market Challenges
High Cost Of Protein A Resin Purification
One of the major factors restricting the Protein A Resin procedures in many countries around the world is owing to high cost of Protein A Resin purification that are obstructing market development during the forecast period 2021-2026. Moreover, with the high demand in the availability of protein A resin the prices are fluctuating for the final product and thereby, facing challenges.
Protein A Resin Market Landscape
Product launches, mergers and acquisitions, joint ventures and geographical expansions are key strategies adopted by players in the Protein A Resin market. In 2020, Protein A Resin market share is fragmented by the top ten players present in the market. The Protein A Resin market top 10 companies are Thermo Fisher Scientific, Repligen, Purolite Life Sciences, Expedeon Ltd, Tosoh Bioscience, EMD Millipore, Novasep, GenScript Biotech Corporation, GE Healthcare and others.
Acquisitions/Product Launches
- In December 2019, World Health Organization (WHO) prequalified its first bio-similar medicine trastuzumab, a monoclonal antibody for the treatment of early stage breast cancer.
Relevant Reports:
Report Code: HCR 0353
Report Code: FBR 0052
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1. Protein A Resin Market - Overview
1.1 Definitions and Scope
2. Protein A Resin Market - Executive Summary
2.1 Market Revenue and Key Trends by Company
2.2 Key trends by Matrix Type
2.3 Key trends by Application
2.4 Key trends by Geography
3. Protein A Resin Market – Comparative Analysis
3.1 Product Benchmarking – Key Companies
3.2 Financial Analysis – Key Companies
3.3 Market Value Split by Key Companies
3.4 Patent Analysis – Key Companies
3.5 Pricing Analysis
4. Protein A Resin Market - Startup Companies Scenario Premium
4.1 Key Startup Company Analysis by
4.1.1 Investment
4.1.2 Revenue
4.1.3 Venture Capital and Funding Scenario
5. Protein A Resin Market – Industry Market Entry Scenario Premium Premium
5.1 Regulatory Framework Overview
5.2 New Business and Ease of Doing business index
5.3 Case Studies of Successful Ventures
6. Protein A Resin Market Forces
6.1 Market Drivers
6.2 Market Constraints/Challenges
6.3 Porters five force model
6.3.1 Bargaining power of suppliers
6.3.2 Bargaining powers of customers
6.3.3 Threat of new entrants
6.3.4 Rivalry among existing players
6.3.5 Threat of substitutes
7. Protein A Resin Market – Strategic Analysis
7.1 Value Chain Analysis
7.2 Opportunities Analysis
7.3 Market Life Cycle
8. Protein A Resin Market - By Matrix Type (Market Size –$Million/$Billion)
8.1 Agarose-based Protein A
8.2 Glass/Silica-based Protein A
8.3 Organic Polymer-based Protein A
9. Protein A Resin Market - By Source Type (Market Size –$Million/$Billion)
9.1 Recombinant Protein A
9.2 Natural Protein A
10. Protein A Resin Market - By Application (Market Size –$Million/$Billion)
10.1 Immunoprecipitation (IP)
10.2 Antibody Purification
11. Protein A Resin Market - By End User (Market Size –$Million/$Billion)
11.1 Biopharmaceutical Manufacturers
11.2 Clinical Research Laboratories
11.3 Academic Institutes
12. Protein A Resin Market - By Geography(Market Size –$Million/$Billion)
12.1 North America
12.1.1 U.S.
12.1.2 Mexico
12.1.3 Canada
12.2 Europe
12.2.1 U.K.
12.2.2 France
12.2.3 Germany
12.2.4 Russia
12.2.5 Italy
12.2.6 Spain
12.2.7 Rest of Europe
12.3 Asia Pacific
12.3.1 China
12.3.2 India
12.3.3 Japan
12.3.4 South Korea
12.3.5 Australia & New Zealand
12.3.6 Rest of APAC
12.4 South America
12.4.1 Brazil
12.4.2 Argentina
12.4.3 Others
12.5 Rest of the World
12.5.1 Middle East
12.5.2 Africa
12.5.3 South America
13. Protein A Resin Market - Entropy
14. Protein A Resin Market – Industry/Segment Competition Landscape Premium
14.1 Market Share Analysis
14.1.1 Global Market Share – Key Companies
14.1.2 Market Share by Region – Key companies
14.1.3 Market Share by Countries – Key Companies
14.1.4 Best Practices for Companies
15. Protein A Resin Market – Key Company List by Country Premium Premium
16. Protein A Resin Market Company Analysis
16.1 Company 1
16.2 Company 2
16.3 Company 3
16.4 Company 4
16.5 Company 5
16.6 Company 6
16.7 Company 7
16.8 Company 8
16.9 Company 9
16.10 Company 10
"*Financials for private companies would be provided on a best efforts basis”.
LIST OF TABLES
1.Global Protein A Resin Market Analysis, By Product Type Market 2023-2030 ($M)1.1 Natural Protein A Resin Market 2023-2030 ($M) - Global Industry Research
1.2 Recombinant Protein A Resin Market 2023-2030 ($M) - Global Industry Research
2.Global Protein A Resin Market Analysis, By End Users Market 2023-2030 ($M)
2.1 Biopharmaceutical Manufacturers Market 2023-2030 ($M) - Global Industry Research
2.2 Clinical Research Laboratories Market 2023-2030 ($M) - Global Industry Research
2.3 Academic Institutes Market 2023-2030 ($M) - Global Industry Research
3.Global Protein A Resin Market Analysis, By Matrix Type Market 2023-2030 ($M)
3.1 Glass or Silica Based Market 2023-2030 ($M) - Global Industry Research
3.2 Agarose-based Market 2023-2030 ($M) - Global Industry Research
3.3 Organic Polymer Based Market 2023-2030 ($M) - Global Industry Research
4.Global Competition Landscape Market 2023-2030 ($M)
5.Global Protein A Resin Market Analysis, By Product Type Market 2023-2030 (Volume/Units)
5.1 Natural Protein A Resin Market 2023-2030 (Volume/Units) - Global Industry Research
5.2 Recombinant Protein A Resin Market 2023-2030 (Volume/Units) - Global Industry Research
6.Global Protein A Resin Market Analysis, By End Users Market 2023-2030 (Volume/Units)
6.1 Biopharmaceutical Manufacturers Market 2023-2030 (Volume/Units) - Global Industry Research
6.2 Clinical Research Laboratories Market 2023-2030 (Volume/Units) - Global Industry Research
6.3 Academic Institutes Market 2023-2030 (Volume/Units) - Global Industry Research
7.Global Protein A Resin Market Analysis, By Matrix Type Market 2023-2030 (Volume/Units)
7.1 Glass or Silica Based Market 2023-2030 (Volume/Units) - Global Industry Research
7.2 Agarose-based Market 2023-2030 (Volume/Units) - Global Industry Research
7.3 Organic Polymer Based Market 2023-2030 (Volume/Units) - Global Industry Research
8.Global Competition Landscape Market 2023-2030 (Volume/Units)
9.North America Protein A Resin Market Analysis, By Product Type Market 2023-2030 ($M)
9.1 Natural Protein A Resin Market 2023-2030 ($M) - Regional Industry Research
9.2 Recombinant Protein A Resin Market 2023-2030 ($M) - Regional Industry Research
10.North America Protein A Resin Market Analysis, By End Users Market 2023-2030 ($M)
10.1 Biopharmaceutical Manufacturers Market 2023-2030 ($M) - Regional Industry Research
10.2 Clinical Research Laboratories Market 2023-2030 ($M) - Regional Industry Research
10.3 Academic Institutes Market 2023-2030 ($M) - Regional Industry Research
11.North America Protein A Resin Market Analysis, By Matrix Type Market 2023-2030 ($M)
11.1 Glass or Silica Based Market 2023-2030 ($M) - Regional Industry Research
11.2 Agarose-based Market 2023-2030 ($M) - Regional Industry Research
11.3 Organic Polymer Based Market 2023-2030 ($M) - Regional Industry Research
12.North America Competition Landscape Market 2023-2030 ($M)
13.South America Protein A Resin Market Analysis, By Product Type Market 2023-2030 ($M)
13.1 Natural Protein A Resin Market 2023-2030 ($M) - Regional Industry Research
13.2 Recombinant Protein A Resin Market 2023-2030 ($M) - Regional Industry Research
14.South America Protein A Resin Market Analysis, By End Users Market 2023-2030 ($M)
14.1 Biopharmaceutical Manufacturers Market 2023-2030 ($M) - Regional Industry Research
14.2 Clinical Research Laboratories Market 2023-2030 ($M) - Regional Industry Research
14.3 Academic Institutes Market 2023-2030 ($M) - Regional Industry Research
15.South America Protein A Resin Market Analysis, By Matrix Type Market 2023-2030 ($M)
15.1 Glass or Silica Based Market 2023-2030 ($M) - Regional Industry Research
15.2 Agarose-based Market 2023-2030 ($M) - Regional Industry Research
15.3 Organic Polymer Based Market 2023-2030 ($M) - Regional Industry Research
16.South America Competition Landscape Market 2023-2030 ($M)
17.Europe Protein A Resin Market Analysis, By Product Type Market 2023-2030 ($M)
17.1 Natural Protein A Resin Market 2023-2030 ($M) - Regional Industry Research
17.2 Recombinant Protein A Resin Market 2023-2030 ($M) - Regional Industry Research
18.Europe Protein A Resin Market Analysis, By End Users Market 2023-2030 ($M)
18.1 Biopharmaceutical Manufacturers Market 2023-2030 ($M) - Regional Industry Research
18.2 Clinical Research Laboratories Market 2023-2030 ($M) - Regional Industry Research
18.3 Academic Institutes Market 2023-2030 ($M) - Regional Industry Research
19.Europe Protein A Resin Market Analysis, By Matrix Type Market 2023-2030 ($M)
19.1 Glass or Silica Based Market 2023-2030 ($M) - Regional Industry Research
19.2 Agarose-based Market 2023-2030 ($M) - Regional Industry Research
19.3 Organic Polymer Based Market 2023-2030 ($M) - Regional Industry Research
20.Europe Competition Landscape Market 2023-2030 ($M)
21.APAC Protein A Resin Market Analysis, By Product Type Market 2023-2030 ($M)
21.1 Natural Protein A Resin Market 2023-2030 ($M) - Regional Industry Research
21.2 Recombinant Protein A Resin Market 2023-2030 ($M) - Regional Industry Research
22.APAC Protein A Resin Market Analysis, By End Users Market 2023-2030 ($M)
22.1 Biopharmaceutical Manufacturers Market 2023-2030 ($M) - Regional Industry Research
22.2 Clinical Research Laboratories Market 2023-2030 ($M) - Regional Industry Research
22.3 Academic Institutes Market 2023-2030 ($M) - Regional Industry Research
23.APAC Protein A Resin Market Analysis, By Matrix Type Market 2023-2030 ($M)
23.1 Glass or Silica Based Market 2023-2030 ($M) - Regional Industry Research
23.2 Agarose-based Market 2023-2030 ($M) - Regional Industry Research
23.3 Organic Polymer Based Market 2023-2030 ($M) - Regional Industry Research
24.APAC Competition Landscape Market 2023-2030 ($M)
25.MENA Protein A Resin Market Analysis, By Product Type Market 2023-2030 ($M)
25.1 Natural Protein A Resin Market 2023-2030 ($M) - Regional Industry Research
25.2 Recombinant Protein A Resin Market 2023-2030 ($M) - Regional Industry Research
26.MENA Protein A Resin Market Analysis, By End Users Market 2023-2030 ($M)
26.1 Biopharmaceutical Manufacturers Market 2023-2030 ($M) - Regional Industry Research
26.2 Clinical Research Laboratories Market 2023-2030 ($M) - Regional Industry Research
26.3 Academic Institutes Market 2023-2030 ($M) - Regional Industry Research
27.MENA Protein A Resin Market Analysis, By Matrix Type Market 2023-2030 ($M)
27.1 Glass or Silica Based Market 2023-2030 ($M) - Regional Industry Research
27.2 Agarose-based Market 2023-2030 ($M) - Regional Industry Research
27.3 Organic Polymer Based Market 2023-2030 ($M) - Regional Industry Research
28.MENA Competition Landscape Market 2023-2030 ($M)
LIST OF FIGURES
1.US Protein A Resin Market Revenue, 2023-2030 ($M)2.Canada Protein A Resin Market Revenue, 2023-2030 ($M)
3.Mexico Protein A Resin Market Revenue, 2023-2030 ($M)
4.Brazil Protein A Resin Market Revenue, 2023-2030 ($M)
5.Argentina Protein A Resin Market Revenue, 2023-2030 ($M)
6.Peru Protein A Resin Market Revenue, 2023-2030 ($M)
7.Colombia Protein A Resin Market Revenue, 2023-2030 ($M)
8.Chile Protein A Resin Market Revenue, 2023-2030 ($M)
9.Rest of South America Protein A Resin Market Revenue, 2023-2030 ($M)
10.UK Protein A Resin Market Revenue, 2023-2030 ($M)
11.Germany Protein A Resin Market Revenue, 2023-2030 ($M)
12.France Protein A Resin Market Revenue, 2023-2030 ($M)
13.Italy Protein A Resin Market Revenue, 2023-2030 ($M)
14.Spain Protein A Resin Market Revenue, 2023-2030 ($M)
15.Rest of Europe Protein A Resin Market Revenue, 2023-2030 ($M)
16.China Protein A Resin Market Revenue, 2023-2030 ($M)
17.India Protein A Resin Market Revenue, 2023-2030 ($M)
18.Japan Protein A Resin Market Revenue, 2023-2030 ($M)
19.South Korea Protein A Resin Market Revenue, 2023-2030 ($M)
20.South Africa Protein A Resin Market Revenue, 2023-2030 ($M)
21.North America Protein A Resin By Application
22.South America Protein A Resin By Application
23.Europe Protein A Resin By Application
24.APAC Protein A Resin By Application
25.MENA Protein A Resin By Application