Digital PCR & Real-time PCR Market - Forecast(2024 - 2030)

Digital PCR & Real-time PCR Market Overview

The Digital PCR & Real-time PCR Market size is forecasted to reach $9.4 billion by 2027 and is expected to grow at a CAGR of 9.6% during the forecast period 2022-2027. In Medical Biotechnology, polymerase chain reaction (PCR) is a strong core molecular biology technique for copying and amplifying a tiny amount of DNA sample in a short period of time. DNA strands, a set of synthetic oligonucleotides primers, a thermostable DNA polymerase, and nucleotides make up a conventional PCR. The method is widely utilized in human genome research. Two of the most common PCR techniques are Real-time PCR (qPCR) and digital PCR (dPCR). Both qPCR and dPCR provide accurate quantification of nucleic acid molecules, however, dPCR is preferred over qPCR due to enhanced precision and its ability to measure microscopic quantitative differences. The Digital PCR & Real-time PCR Market is being driven due to the surge in diseases and genetic disorders. The market also got a significant boost during the Corvid 19 Pandemic where Real-time PCR has deemed the gold standard of testing, and organizations such as the International Atomic Energy Agency (IAEA) and the Food and Agriculture Organization (FAO) provided support to countries related to the adoption of the technique. These are some of the factors driving the growth of the market in the forecast period 2022-2027.

Digital PCR & Real-time PCR Market Report Coverage

The report: “Digital PCR & Real-time PCR Market Forecast (2022-2027)”, by Industry ARC, covers an in-depth analysis of the following segments of the Digital PCR & Real-time PCR Market.

By Type: Real-time PCR(qPCR), Digital PCR (Droplet Digital PCR (ddPCR), Microfluidics-based digital quantitative PCR (qdPCR))
By Product Type: Reagents and Kits (DNA Template, DNA Polymerase, Primers, Nucleotides), Software, Instruments (Conventional PCR machine, qPCR machine, Digital PCR machine, Others), Consumables
By Applications: Medical Diagnostics, Research, Forensic Investigations, Others
By End Users: Research Laboratories, Hospitals and Clinics, Pharmaceutical Companies, Biotechnological Companies
By Geography: North America (U.S, Canada, Mexico), South America (Brazil, Argentina, Colombia, Chile, Rest of South America), Europe (U.K, Germany, Italy France, Spain, Netherlands, Russia, Rest of Europe), Asia Pacific (China, India, Japan, Australia & New Zealand, South Korea, Rest of Asia Pacific), Rest of the World (Middle East and Africa)

Key Takeaways

• As per a survey conducted by a key player, Geographically, The North American Digital PCR & Real-time PCR Market accounted for the highest revenue share in 2021. This is owing to the highly developed healthcare infrastructure in the region. In addition, the region has received funding from government institutes for research on qPCR and dPCR devices.
• Several key players across several regions, such as Bio-Rad are heavily investing in Digital PCR and Real-time PCR R&D. For instance, Bio-Rad has been consistently researching ddPCR Genome Edit Detection Assays, which can help scientists evaluate modifications by genome editing tools.
• Digital PCR & Real-time PCR Market Detailed Analysis on the Strength, Weakness, and Opportunities of the prominent players operating in the market will be provided in the Digital PCR and Real-time PCR Market report.

Digital PCR & Real-time PCR Market Segment Analysis – By Type

The Digital PCR & Real-time PCR Market based on type can be segmented into Real-time PCR(qPCR) and Digital PCR (Droplet Digital PCR (ddPCR), Microfluidics-based digital quantitative PCR (qdPCR). Real-time PCR held the largest share in the Digital PCR & Real-time PCR Market in 2021 and is growing at a CAGR of 8.2% during the forecast period of 2022-2027. Real-time PCR is a well-established technique and enjoys constant demand from microbiological laboratories. It is further driven by the ease of testing that Real-time PCR instruments provide over traditional PCR instruments. As per recent estimates, Real-time PCR demand reached an all-time high in 2021 due to the increase in cases of Covid 19 with Real-time PCR kits specializing in Covid testing, being shipped to several countries worldwide. However, Digital PCR is estimated to be the fastest-growing segment during the forecast period of 2022-2027 owing to its increased precision over traditional methods. dPCR is also being preferred for the detection of rare sequences such as deep-rooted cancer and mutations.

Digital PCR & Real-time PCR Market Segment Analysis – By Application

The Digital PCR & Real-time PCR Market based on Application can be segmented into Medical Diagnostics, Research, Forensic Investigations, and Others. Research held the largest share in the Digital PCR & Real-time PCR Market in 2021 growing at a CAGR of 8.8% during the forecast period of 2022-2027. This is owing to their extensive application in medical and biological research facilities. The techniques are also used in Phylogenetical studies which involve the use of ancient DNA. PCR also enjoys a significant market in the area of Genetic research involving genetic modification and genetic engineering. However, Medical Diagnostic is estimated the fastest-growing segment during the forecast period of 2022-2027. This is owing to their contribution to medicine development across several disciplines. qPCR and dPCR are also used for medicinal research into the diagnosis, treatment, and cure across several disciplines.

Digital PCR & Real-time PCR Market Segment Analysis – By Geography

The Global Demand for Digital PCR & Real-time PCR Market based on Geography can be segmented into North America, South America, Europe, Asia-Pacific, and Rest of the World. The North America region dominated the Digital PCR & Real-time PCR Market in 2021 with a market share of 39%. This is owing to the extensive R&D carried out by the companies in the region. North America also regularly receives funding from Government institutions such as the National Institute of Health (NIH), for the development of qPCR and dPCR instruments. The region is also riddled with Cancer patients with over 1.9 million new cases in 2021. As per government websites, the region spent over $210 billion on cancer care and research. The rising prevalence and cancer and investment in cancer care and research have driven the market in the region.

However, Asia Pacific is estimated to be the fastest-growing segment during the forecast period of 2022-2027 owing to the rapid improvement in healthcare systems. As per Mckinsey, the other major factor driving the Digital PCR & Real-time PCR Market in the region is an increasing geriatric population. Asia is set to have almost 450 million people over the age of 65 within 2025, which is around a 15% increase from 2021.

Digital PCR & Real-time PCR Market Drivers

Rising Incidences of Different Diseases and Genetic Disorders are driving the Market Growth

A study by the Journal of the Royal Society Interface shows that disease levels have risen significantly since 1980, with almost 30% of the diseases being the cause of 80% of outbreaks. Genetic disorders have also become prevalent in recent times with the World Health Organization (WHO) stating that it accounts for over 28% of hospital admissions and is also responsible for almost 50% of childhood deaths. qPCR and dPCR are the preferred techniques for use in prenatal diagnosis and carrier testing of several genetic disorders. qPCR has always been influential in the investigation of bacteria and viruses to diagnose diseases while dPCR, in spite of being an emerging technology has been able to enhance the detection of extremely precise gene mutations. This has propelled the market for Real-time and Digital PCR.

The capabilities of qPCR testing in the detection of SARS-CoV-2 are driving the Market Growth

Effective testing has been paramount for controlling the spread of Covid 19 and the qPCR tests have been effective in the detection of the SARS-COV-2 virus. Using qPCR testing techniques, doctors and researchers have been able to detect genetic information with to an extent of 1000 copies of viral RNA per milliliter. Due to its success, organizations such as UNICEF have entered into a financial agreement worth over $60 million in order to distribute affordable and large quantities of qPCR tests worldwide. Naturally, the demand for qPCR and dPCR was boosted as a result.

Digital PCR & Real-time PCR Market Challenges

High cost of Digital PCR and Real-time PCR equipment is hampering the market growth

Equipment and tools necessary to carry out PCR tests tend to be on the higher side, especially in the case of dPCR equipment. As per several sources, a dPCR or qPCR machinery can cost anywhere between $15,000 to upwards of $100,000. Other than the high initial costs, there are hidden costs such as the operational cost of cyclers which are incurred every year and the cost of a universal probe mastermixes. The high costs of the equipment may hamper the market growth, especially in developing and developed economies.

Digital PCR and Real-time PCR Industry Outlook

Product Launch and Acquisitions were the key strategies adopted by players in the Digital PCR & Real-time PCR Market. In 2022, the Digital PCR & Real-time PCR Market share is consolidated by the top ten players present in the market. Digital PCR and Real-time PCR top 10 companies include: -

1.  Abbott Laboratories
2. Bio-Rad Laboratories, Inc.
3. F. Hoffman-La Roche Ltd.
4.  Biomérieux S.A
5. Qiagen N.V.
6. Becton Dickinson and Company
7.  Agilent Technologies, Inc.
8. Thermo Fisher Scientific Inc.
9. Enzo Life Sciences, Inc.
10. Quanta Biosciences Inc.

Recent Developments

• In October 2021, Bio-Rad Laboratories, Inc. announced the launch of their CFX Opus 96 Dx System and CFX Opus 384 Dx System. The new instruments will provide real-time PCR detection for in-vitro diagnostics testing.
• In September 2021, Thermo Fisher Scientific announced the launch of QuantStudio Absolute Q Digital PCR System, which is capable of providing accurate results within 90 minutes. 
• In March 2021, Thermo Fisher launched the QuantStudio 5 Dx Real-Time PCR System. The products will be used by clinical laboratories and assay developers to fulfill innovative tests and improve molecular diagnostics workflows.
  

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