Biosimulation Market size is expected to reach $49.2 billion by 2030 after growing at a CAGR of 9.4% during the forecast period 2024-2030, according to the latest market research report published by IndustryARC. Increasing incidence of Cancer, Rising cases of the chronic diseases and the increasing investment in healthcare are set to drive the Biosimulation market, finds IndustryARC in its recent report, titled “Biosimulation Market - By Type (Software, Services), By Application ( Preclinical and Clinical Development, Drug Discovery), By End Use (Academic and Government Research Institutes, Pharmaceuticals and Biotechnological Companies, Contract Research Organizations, Regulatory Authorities) and By Geography Analysis - Global Opportunity Analysis & Industry Forecast, 2024-2030

Rise in Chronic Diseases to Boost Market Growth
Chronic diseases are a major public health challenge, but they are preventable. There are a number of things that individuals and governments can do to reduce the burden of chronic diseases, such as promoting healthy lifestyles, improving access to healthcare, and investing in research. As people live longer, they are more likely to develop chronic diseases. The shift from rural to urban living is associated with an increase in risk factors for chronic diseases, such as unhealthy diet, physical inactivity, and tobacco use. The spread of Western lifestyles, including high-fat, high-sugar diets and tobacco use, is contributing to the rise of chronic diseases in low- and middle-income countries. The World Health Organization (WHO) warns that NCDs, including cardiovascular diseases, cancer, diabetes, and respiratory illnesses, will account for 86% of the 90 million deaths annually by 2050. This represents a staggering 90% increase in absolute numbers since 2019.

Biosimulation Market 2024-2030: Segmentation

By Type
Software
Services

By Application 
Preclinical and Clinical Development, Drug Discovery
Preclinical and Clinical Development
Drug Discovery

By End User
Academic and Government Research Institutes
Pharmaceuticals and Biotechnological Companies
Contract Research Organizations
Regulatory Authorities

By Region
North America
South America
Europe
Asia-Pacific
Rest of the World

Biosimulation Market Report – Key Takeaways:

North America Leading the Market
Geographically, North America held the largest share with 35% of the overall market in 2023, North America's dominant position in the biosimulation market is a result of a combination of factors, including a robust pharmaceutical industry, technological leadership and supportive regulatory environment. In December 2023, Pfrized completed a $43 billion acquisition of cancer and antibody-drug conjugate biologic company, Seagen. By 2030, Pfizer expects biologics such as antibody-drug conjugates (ADCs) and bispecific antibodies to contribute approximately 65% of its oncology revenues, up from 6% in 2023, a more than 10-fold increase, as per the company’s Oncology Innovation Day Presentation in February 2024. 

Increasing Drug Relapse
Drug relapse is a significant challenge in many therapeutic areas, including cancer, infectious diseases, and mental health. Biosimilars with their ability to model complex biological systems, offer a promising avenue to understand the mechanisms underlying relapse and develop strategies to prevent it. Biosimulation can be used to predict the likelihood of relapse based on patient-specific factors, such as tumor characteristics or genetic makeup. Biosimulation can contribute to the development of immune checkpoint inhibitors by modeling their impact on anti-tumor immunity and resistance mechanisms. It can help monitor minimal residual disease (MRD) and develop strategies to eradicate residual cancer cells.

Disease Modelling
Biosimulation is a powerful tool for understanding the complex dynamics of diseases. By simulating biological processes within a computational environment, researchers can gain insights into disease progression, transmission, and potential treatment strategies. Individual-based models (IBMs) focus on simulating the behavior of individual organisms, including their interactions with the environment and other individuals. These models are particularly useful for studying infectious diseases and population dynamics.  Agent-based models (ABMs) are similar to IBMs but with a greater emphasis on the interactions between agents, which can represent individuals, cells, or even molecules. ABMs are often used to model complex systems, such as tumor growth or immune response.

Key Opportunity Analysis: 

Advancements in AI and ML
The intersection of AI and ML with Biosimulation is a rapidly evolving field with immense potential. By leveraging the power of these technologies, researchers and scientists are making significant strides in understanding complex biological systems, accelerating drug discovery, and improving healthcare outcomes. AI can automatically create complex biological models, optimize their parameters, and validate their accuracy. ML extracts meaningful information from biological data, integrates diverse datasets, and predicts future biological outcomes. AI identifies drug targets, screens compound, repurposes existing drugs, and improves drug behavior modeling. ML analyzes patient data to identify subgroups, optimize treatments, and deliver tailored healthcare.

Antibiotic Resistance
According to the Environmental Working Group, by 2048 antibiotic resistance could cause more casualties than cancer. Biosimulation can play a crucial role in addressing antibiotic resistance by by modeling the evolutionary dynamics of bacteria, researchers can anticipate which antibiotics might become ineffective. Biosimulation can help in the design of novel antibiotics by simulating their interactions with bacterial targets. By modeling the pharmacokinetics and pharmacodynamics of antibiotics, researchers can determine optimal dosing and treatment durations to minimize the risk of resistance.

The Report also Covers the Following Areas:
Biosimulation Market size and Forecast 
Biosimulation Market trends
Biosimulation Market analysis by type

2023-2030: Key Highlights
CAGR of the market during the forecast period 2024-2030
Value Chain analysis of key stake holders
Detailed analysis of market drivers and opportunities during the forecast period
Biosimulation Market size estimation and forecast
Analysis and predictions on end user behavior and upcoming trends 
Competitive landscape and Vendor market analysis including offerings, developments, and financials
Comprehensive analysis of challenges and constraints in the Biosimulation Market

Biosimulation Market Players:

The companies profiled in the Biosimulation Market include:
Novartis
Pfizer 
Catalent 
Amgen
Biogen
Patheon
Shanghai Henlius Biotech
Vaitris
Celltrion
Samsung Bioepis
ACD/Labs
Schrödinger
Physiomics
LeadInvent Technologies 
Rosa

Related Reports:

Biomarkers Market – Biomarkers are biological molecules which act as indicator of a particular disease state or pharmacological conditions. Advancement in post genomic technologies, increasing R&D spending and dynamic applications of biomarkers in medicine will drive the future market growth.

Bioinformatics Market- Bioinformatics Market size was valued at $8.3 billion in 2020, growing at a CAGR of 12.4% during the forecast period. The recording, annotation, storage, analysis, and retrieval of nucleic acid sequence, protein sequence, and structural information are all covered by bioinformatics.
 
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